In 680 C.E., the Muslim world shook to its foundations by the tragedy of Karbala. The tragedy of Karbala would bot have taken place if Uthman had not been assassinated. If Uthman had not been assassinated and he had died a natural death, he was likely to be succeeded by Ali. In that case there would have been no Ali-Muawiyah conflict for the conflict merely arose because of the demand for the vengeance of the blood of Uthman. In the absence of such a conflict, Ali would not have been assassinated and the Umayyads would not have come into power. As such there would have been no occasion for the tragedy of Karbala.
"When a person dies, his works end, except for three: ongoing charity, knowledge that is benefited from, and a righteous child who prays for him."
Prophet Mohammed (PBUH)
"The best of what a man leaves behind are three: a righteous child who supplicates for him, ongoing charity the reward of which reaches him, and knowledge that is acted upon after him."
Sunan Ibn Mājah
"Every day two angels come down from Heaven and one of them says, 'O Allah! Compensate every person who spends in Your Cause,' and the other (angel) says, 'O Allah! Destroy every miser.'"
Sahih Bukhari